Faculty

Ginés Escolar

M.D., Ph.D.

Senior Consultant of Hemotherapy and Hemostasis, Hospital Clínic, Barcelona, Spain. Retired Professor of Hematology, Department of Medicine, Universitat de Barcelona. Director of the Platelet Research Laboratory.

Research

  • Platelet physiology and pathology.
  • Congenital and acquired bleeding disorders.
  • Thrombosis, atherosclerosis and vascular injury.
  • Pharmacological management of haemostasis.
  • Quality control of platelet concentrates; Development on synthetic alternatives.
  • Artificial surfaces; blood biocompatibility.

Clinical Service

  • Provides diagnostic and follow-up advice for patients with bleeding problems and rare platelet disorders.

Techniques

Publications

Click here to link the full list of publications of Ginés Escolar in MedLine

Maribel Díaz-Ricart

Ph.D.

Pharmacist, Research Coordinator. Laboratory of Platelet and Vascular Biology Research.

Research

  • Platelet biochemistry and physiology.
  • Platelet activation and signaling mechanisms associated with cytoskeletal proteins.
  • Signal transduction mechanisms in platelets activated by adhesion to adhesive substrata under flow conditions.
  • Mechanisms of disease in Thrombotic MicroAngiopathies (TMA)
  • Models of endothelial dysfunction
  • Adhesion studies and signaling mechanisms in CD34+ hematopoietic progenitors.
  • Signaling pathways in endothelial cells.
  • Mechanisms of endothelial dysfunction. Study of potential preventive strategies.

Techniques

  • Isolation of cells from tissues and cell cultures.
  • Techniques to explore platelet function.
  • Annular, parallel and microchamber perfusion systems. Morphometric techniques.
  • Light and confocal microscopy.
  • Protein isolation and protein evaluation techniques.
  • Proteomic analysis.
  • Coagulometric and thromboelastometric techniques.
  • Writing and editing of scientific texts.

Publications

Click here to link the full list of publications of Maribel Díaz-Ricart in MedLine.

Marta Palomo

Ph.D.

Biologist. Postdoctoral fellow and Science journalist. Josep Carreras Insitute against Leukaemia. Researcher of the Platelet Research Laboratory.

Research

  • Complement system dysregulation and thrombotic microangiopathies
  • Endothelial physiology and dysfunction.
  • Signaling pathways in endothelial cells.
  • Pharmacological management of endothelial dysfunction.
  • Platelet biochemistry and physiology.
  • Thrombosis, atherosclerosis and vascular injury.

Techniques

  • Isolation of cells from tissue and cell cultures.
  • Angiogenesis and wound healing assays.
  • SDS-PAGE. Western-blot. Immunoprecipitation.
  • Biomarkers (ELISA).
  • Flow cytometry.
  • Platelet aggregometry.
  • Annular and parallel chamber perfusion systems. Morphometric techniques.
  • Morphology: light microscopy, and confocal fluorescence microscopy.
  • Digital image analysis.

Publications

Click here to link the full list of publications of Marta Palomo in MedLine

Marc Pino

 Technician

Laboratory Technician. Graduate of Speciallyzed Technician in Clinical Analysis (Institut Pedraforca). Researcher of the Platelet Research Laboratory.

Techniques

  • Laboratory tests on primary hemostasis and coagulation: Platelet aggregometry, PFA-100® Analyzer.
  • Thromboelastography.
  • Cell cultures.
  • Light microscopy.
  • Flow cytometry.
  • Annular, flat and microchamber perfusion systems.
  • Protein techniques: isolation, resolution and identification.

Publications

Click here to link the full list of publications of Marc Pino in MedLine

Patricia Molina Moreno

Technician

Laboratory Technician. Graduate of Speciallyzed Technician in Clinical Analysis (Institut Dolmen). Researcher of the Platelet Research Laboratory.

Techniques

  • Laboratory tests on primary hemostasis and coagulation: Platelet aggregometry, PFA-100® Analyzer.
  • Inmunocytochemistry.
  • Thromboelastography.
  • Cell cultures.
  • Light and fluorescence microscopy.
  • Flow cytometry.
  • Annular, flat and microchamber perfusion systems.
  • Protein techniques: isolation, resolution and identification.

Publications

Click here to link the full list of publications of Patricia Molina in MedLine

Júlia Martínez Sánchez

Ph.D. Student

Ph. D. student. Josep Carreras Insitute against Leukaemia. Master’s degree in Translational Medicine. Graduate of Human Biology.

Research

  • Endothelial cells in culture.
  • Signaling pathways in endothelial cells.
  • Endothelial damage in hematopoietic stem cell transplantation.
  • Pharmacological management of endothelial dysfunction.

 Techniques

  • Isolation of cells from tissue and cell cultures.
  • Angiogenesis and wound healing assays.
  • SDS-PAGE. Western-blot. Immunoprecipitation.
  • Soluble biomarkers (ELISA).
  • Flow cytometry.
  • Annular and parallel chamber perfusion systems. Morphometric techniques.
  • Microfluidic adhesion studies.
  • Morphology: light microscopy, and confocal fluorescence microscopy.
  • Image digital analysis.

Publications

Click here to link the full list of publications of Julia Martinez in MedLine

Ana Belén Moreno-Castaño

M.D., Ph.D. Student

Hematologist. Pre-doctoral fellow and researcher in Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Platelet Research Laboratory, Hospital Clinic Barcelona.

Research

  • Endothelial physiology and dysfunction.
  • Signaling pathways in endothelial cells.
  • Platelet biochemistry and physiology.
  • Atherosclerosis and vascular injury.
  • Thrombosis, bleeding and fibrinolytic dysfunction in diverse clinical conditions.
  • Pharmacological management of endothelial dysfunction and hemorrhagic diathesis.
  • Eritropathology.

Techniques

  • Isolation of cells from tissue and cell cultures.
  • Angiogenesis and wound healing assays.
  • SDS-PAGE. Western-blot.
  • Biomarkers by Enzyme-linked immunosorbent assay.
  • Flow cytometry.
  • Platelet aggregometry.
  • Evaluation of platelet’s granule release
  • Annular and parallel chamber perfusion systems. Morphometric techniques.
  • Morphology: light microscopy and confocal fluorescence microscopy.
  • Image digital analysis.
  • Coagulometric and thromboelastometric techniques.
  • Molecular diagnosis by Sanger PCR sequencing and GAP-PCR.

Publications

Click here to link the full list of publications of Ana Belén Moreno-Castaño in MedLine

Alex Ramos

Ph.D. Student

Pharmacist. Predoctoral. Josep Carreras Insitute against Leukaemia. Researcher of the Platelet Research Laboratory.

Research interest

  • Endothelial physiology and dysfunction.
  • Signaling pathways in endothelial cells.
  • Pharmacological management of endothelial dysfunction.
  • Thrombosis, atherosclerosis and vascular injury.
  • Endothelial damage in preeclampsia.
  • Role of extracellular vesicles in pathology.

Techniques

  • Isolation of cells from tissue and cell cultures.
  • Angiogenesis and wound healing assays.
  • SDS-PAGE. Western-blot. Immunoprecipitation.
  • Biomarkers (ELISA).
  • Flow cytometry.
  • Platelet aggregometry.
  • Annular and parallel chamber perfusion systems. Morphometric techniques.
  • Morphology: light microscopy, and confocal fluorescence microscopy.
  • Image digital analysis.

Publications

Click here to link the full list of publications of Alex Ramos in MedLine

Jordi Bozzo

Ph.D., C.M.P.P.

Biologist, Medical Writer and Web Coordinator. Platelet Research Laboratory.

Research Interest

  • Effect of drugs on platelet-erythrocyte interactions.
  • Study of platelet-subendothelium interactions: effects of drugs on platelet deposition: Inhibitors of platelet function, non-steroidal antinflammatory drugs, NO-donors.
  • Blood rheology.
  • Disease cross-talk: interaction and interdependence among diseases, including thrombosis, Alzheimer’s disease, cancer, immune system diseases.
  • Signal transduction, metabolic pathways and therapeutic targets: pathophysiological cellular and molecular interactionsl in drug treatments.

Techniques

Computing

  • Medical illustration & artwork.
  • Scientific multimedia applications.
  • Web design, webmastering.

Medical writting

  • ISMPP Certified Medical Publications Professional

Publications

Click here to link the full list of publications of Jordi Bozzo in MedLine

 Montse Riego

Attorney at Law

Legal advisor and Grants administrator. Platelet Research Laboratory.