Maribel Díaz-Ricart, Ph.D.

Pharmacist, Research Coordinator. Platelet Research Laboratory.

Research Interest

• Platelet biochemistry and physiology.
• Platelet activation and signaling mechanisms associated to the cytoskeleton.
• Signal transduction mechanisms in platelets activated by adhesion to adhesive substrata under flow conditions.
• Signaling pathways in endothelial cells.
• Adhesion studies and signaling mechanisms in CD34+ hematopoietic progenitors.

Techniques

• Isolation of cells from tissue and cell cultures.
• Platelet aggregometry.
• Annular and parallel chamber perfusion systems. Morphometric techniques.
• Protein isolation and protein techniques.
• Electrophoresis and Immuno-blot.

Selected publications

• Fuste B, Mazzara R, Escolar G, Merino A, Ordinas A, Diaz-Ricart M. Granulocyte colony-stimulating factor increases expression of adhesion receptors on endothelial cells through activation of p38 MAPK. Haematologica 2004;89:578-85.
• Fuste B, Escolar G, Marin P, Mazzara R, Ordinas A, Diaz-Ricart M. G-CSF increases the expression of VCAM-1 on stromal cells promoting the adhesion of CD34+ hematopoietic cells: studies under flow conditions. Exp Hematol 2004;32:765-72.
• Gomez-Gil E, Gasto C, Carretero M, Diaz-Ricart M, Salamero M, Navines R, Escolar G. Decrease of the platelet 5-HT2A receptor function by long-term imipramine treatment in endogenous depression. Hum Psychopharmacol 2004;19:251-8.
• Zurbano MJ, Fuste B, Arderiu G, Escolar G, Ordinas A, Diaz-Ricart M. Differences and similarities in tyrosine phosphorylation of proteins in platelets from human and pig species. J Thromb Haemost 2003;1:2411-8.
• Arderiu G, Diaz-Ricart M, Aznar-Salatti J, Escolar G, Ordinas A. A von Willebrand factor/factor VIII complex restores platelet adhesion and fibrin formation in type 3 von Willebrand syndrome. J Thromb Haemost 2003;1:865-6.
• Merino A, Mazzara R, Fuste B, Diaz-Ricart M, Rozman M, Lozano M, Ordinas A. Transfusion medicine illustrated. The mesenchymal stem cell revealed. Transfusion 2003;43:1.

Click here to link the full list of publications of Maribel Díaz-Ricart in MedLine.